Low-Grade Squamous Intraepithelial Lesion/Cannot Exclude High-Grade Squamous Intraepithelial Lesion (LSIL-H) Is a Unique Category of Cytologic Abnormality Associated With Distinctive HPV and Histopathologic CIN 2+ Detection Rates

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Low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion: a category with an increased outcome of high-grade lesions: use as a quality assurance measure.

"Low-grade squamous intraepithelial lesion (LSIL), cannot exclude high-grade squamous intraepithelial lesion" (LSIL-H) is an increasingly used, equivocal interpretive category in gynecologic cytology. In an effort to evaluate its potential usefulness as a measure of quality assurance, we studied patterns of use of the LSIL-H diagnosis compared with "LSIL" and "high-grade squamous intraepithelia...

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Human papillomavirus viral load in predicting high-grade CIN in women with cervical smears showing only atypical squamous cells or low-grade squamous intraepithelial lesion.

CONTEXT Human papillomavirus (HPV) viral load may have an important role in predicting high-grade cervical intraepithelial neoplasia (CIN) in women with cervical smears showing atypical squamous cells or LSIL. OBJECTIVE To determine whether the assessment of the viral load of high-risk HPV DNA is useful in predicting the detection of high-grade cervical intraepithelial neoplasia (CIN2 and 3) ...

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High-grade squamous intraepithelial lesion (HSIL) smear is one of the categories of squamous cell abnormality in the 2001 Bethesda System. HSIL denotes cases who have abnormal squamous cells with an increased nuclear/ cytoplasmic ratio, marked atypical nucleus, and irregular nuclear border (Wright et al., 2011). At the present, HSIL is acknowledged as a high-grade cervical smear abnormality. Ac...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2014

ISSN: 1943-7722,0002-9173

DOI: 10.1309/ajcpm9x5rczyeqjq